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Reactive intermediate chemistry /
Published 2004Table of Contents: “…Crossing the borderline between SN1 and SN2 nucleophilic substitution at aliphatic carbon /…”
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Reactive intermediate chemistry /
Published 2004Table of Contents: “…Crossing the borderline between SN1 and SN2 nucleophilic substitution at aliphatic carbon /…”
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Organic Chemistry : Fundamentals and Concepts /
Published 2018Table of Contents: “…More Stereochemistry and Another Reaction Type {u2013} Nucleophilic Substitution --…”
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Triazines : synthesis, applications, and toxicity /
Published 2012Table of Contents: “…Nucleophilic Substitution of Trinitromethyl Groups""; ""2.1.1.1. …”
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Asymmetric organocatalysis : from biomimetic concepts to applications in asymmetric synthesis /
Published 2005Table of Contents: “…Organocatalysis : from biomimetic concepts to powerful methods for asymmetric synthesis -- On the structure of the book, and a few general mechanistic considerations -- Nucleophilic substitution at aliphatic carbon -- Nucleophilic addition to electron-deficient C=C double bonds -- Nucleophilic addition to C=N double bonds -- Nucleophilic addition to C=O double bonds -- Nucleophilic addition to unsaturated nitrogen -- Cycloaddition reactions -- Protonation of enolates and tautomerization of enols -- Oxidation -- Reduction of carbonyl compounds -- Kinetic resolution of racemic alcohols and amines -- Desymmetrization and kinetic resolution of anhydrides, desymmetrization of meso-epoxides and other prochiral substrates -- Large-scale applications of organocatalysis.…”
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Organic Chemistry with a Biological Emphasis
Published 2016Table of Contents: “…Predicting the mechanism -- Section 7: Biological nucleophilic substitution reactions -- Section 8: Nucleophilic substitution in the lab…”
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Advanced organic chemistry : reaction mechanisms /
Published 2002Table of Contents: “…Radical Substitution Reactions at the Saturated C Atom -- Nucleophilic Substitution Reactions at the Saturated C Atom -- Additions to the Olefinic C=C Double Bond -- Eliminations -- Substitution Reactions on Aromatic Compounds -- Nucleophilic Substitution Reactions (Except Through Enolates) on the Carboxyl Carbon -- Additions of Heteroatom Nucleophiles to Heterocumulenes -- Additions of Heteroatom Nucleophiles to Carbonyl Compounds and Their Secondary Reactions -- Addition of H Nucleophiles and Metal Organyls to Carbonyl Compounds -- Reaction of Ylides with Saturated or Unsaturated Carbonyl Compounds -- Chemistry of the Alkaline Earth Metal Enolates -- Rearrangements -- Thermal Cycloadditions -- Transition Metal-Mediated Alkenylations, Arylations and Alkynylations -- Oxidations and Reductions.…”
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Side reactions in organic synthesis : a guide to successful synthesis design /
Published 2005Table of Contents: “…. -- Aliphatic nucleophilic substitutions : problematic electrophiles. -- The alkylation of carbanions. -- The alkylation of heteroatoms. -- The acylation of heteroatoms. -- Palladium-catalyzed C-C bond formation. -- Cyclizations. -- Monofunctionalization of symmetric difunctional substrates.…”
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Catalytic asymmetric Friedel-Crafts alkylations /
Published 2009Table of Contents: “…General aspects and historical background -- Michael addition -- Addition to carbonyl compounds -- Nucleophilic allylic alkylation and hydroarylation of allenes -- Nucleophilic substitution on Csp³ carbon atoms -- Unactivated alkenes -- Catalytic asymmetric Friedel-Crafts alkylations in total synthesis -- Industrial Friedel-Crafts chemistry.…”
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Progress in physical organic chemistry.
Published 1968Table of Contents: “…PHYSICAL ORGANIC CHEMISTRY; Contents; Barriers to Internal Rotation about Single Bonds.; Nucleophilic Substitution at Sulfur.; Group Electronegativities.; Substituent Effects in the Naphthalene Series. …”
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Organic Reaction Mechanisms 2016 : an Annual Survey Covering the Literature Dated January to December 2016 /
Published 2020Table of Contents: “…Propargyl and Vinyl Carbocations -- Asymmetric Synthesis -- Biosynthetic Chemistry -- References -- Chapter 7 Nucleophilic Aliphatic Substitution -- SN Reactions Forming C-C Bonds -- Allylic Substitutions -- Vinyl Substitutions -- Propargylic Substitutions -- Reactions of Cyclic Ethers -- Aziridines and Other Small Ring Substitution Reactions -- Studies Using Kinetic Isotope Effects -- Nucleophilic Substitution on Elements Other than Carbon -- Medium Effects/Solvent Effects -- Structural Effects -- Theoretical Studies -- Miscellaneous Kinetic and Product Studies -- Other -- Acknowledgement…”
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Organic chemistry /
Published 2023Table of Contents: “…Structure and bonding -- Polar covalent bonds ; acids and bases -- Organic compounds : alkanes and their stereochemistry -- Organic compounds : cycloalkanes and their stereochemistry -- Stereochemistry at tetrahedral centers -- An overview of organic reactions -- Alkenes : structure and reactivity -- Alkenes : reactions and synthesis -- Alkynes : an introduction to organic synthesis -- Organohalides -- Reactions of alkyl halides : nucleophilic substitutions and eliminations -- Structure determination : mass spectrometry and infrared spectrometry -- Appendices -- Answer key -- Index…”
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Organic Chemistry I
Published 2021Table of Contents: “…Chapter 1 Basic Concepts in Chemical Bonding and Organic Molecules -- Chapter 2 Fundamental of Organic Structures -- Chapter 3 Acids and Bases: Organic Reaction Mechanism Introduction -- Chapter 4 Conformations of Alkanes and Cycloalkanes -- Chapter 5 Stereochemistry -- Chapter 6 Structural Identification of Organic Compounds: IR and NMR Spectroscopy -- Chapter 7 Nucleophilic Substitution Reactions -- Chapter 8 Elimination Reactions -- Chapter 9 Free Radical Substitution Reaction of Alkanes -- Chapter 10 Alkenes and Alkynes…”
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Progress in heterocyclic chemistry. a critical review of the 1998 literature preceded by two chapters on current heterocyclic topics /
Published 1999Table of Contents: “…Recent Advances in the Reaction of Metalated Aromatic Heterocycles with Carbonyl Compounds and their Imino Derivatives (P. Merino). Nucleophilic Substitution of C-Hydrogen on the Five-Membered Ring of Indoles (J.A. …”
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Lecture notes on fullerene chemistry : a handbook for chemists /
Published 1999Table of Contents: “…Introduction -- The structure and properties of fullerenes -- Addition patterns -- Hydrogenation -- Reduction by electron addition, and reaction of fullerene radical anions with electrophiles -- Nucleophilic addition, and reaction of fullerene anions with electrophiles -- Radical reactions -- Nucleophilic substitution of fullerenes: fullerenes as electrophiles -- Cycloadditions -- Oxidation and the formation of radical cations and cations -- Inorganic and organometallic derivatives of fullerenes -- Polymers, dendrimers, dimers, dumb-bells and related structures.…”
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Piperidine-based drug discovery /
Published 2017Table of Contents: “…Synthesis of Piperidin-4-Ones by Dieckmann CondensationSynthesis of Piperidin-4-Ones by Miscellaneous Methods; Nucleophilic Addition Reactions to the Carbonyl Group of Piperidin-4-Ones; Nucleophilic Substitution Reactions Involving [alpha]-Carbon of Piperidin-4-Ones; Piperidin-3-Ones; Piperidin-2-Ones; 4-Cyano-4-Phenylpiperidines; References; 2. 1-Substituted Piperidines; 2.1 Derivatives of 1-Phenyl-3-(Piperidin-1-yl)Propan-1-ol; Trihexyphenidyl (2226); Biperiden (1329); Pridinol (157); Cycrimine (82); 2.2 Derivatives of 1-Phenyl-4-(Piperidin-1-yl)Butan-1-ol; Diphenidol (323); Pirmenol (234)…”
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Practical synthetic organic chemistry : reactions, principles, and techniques /
Published 2020Table of Contents: “…Aliphatic nucleophilic substitution -- Addition to carbon-heteroatom multiple bonds -- Addition to carbon-carbon multiple bonds -- Nucleophilic aromatic substitution -- Electrophilic aromatic substitution -- Selected catalytic reactions -- Rearrangements -- Eliminations -- Reductions -- Oxidations -- Selected free radical reactions -- Synthesis of "nucleophilic" organometallic reagents -- Synthesis of common aromatic heterocycles -- Access to chirality -- Biocatalysis -- Green chemistry -- Continuous chemistry -- General solvent properties -- Practical chemistry concepts: tips for the practicing chemist or things they don't teach you in school.…”
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Structure correlation /
Published 1994Table of Contents: “…Structure Correlation; Contents; Part I Basics; 1 Molecular Structure and Coordinate Systems; 2 Symmetry Aspects of Structure Correlation; 3 Crystallographic Databases: Search and Retrieval of Information from the Cambridge Structural Database; 4 Statistical and Numerical Methods of Data Analysis; 5 Structure Correlation; the Chemical Point of View; Part II Molecular Structure and Reactivity; 6 Organic Addition and Elimination Reactions; Transformation Paths of Carbonyl Derivatives; 7 Reaction Paths for Nucleophilic Substitution(SN2)Reactions.…”
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Handbook of Organic Name Reactions : Reagents, Mechanism and Applications.
Published 2023Table of Contents: “…1.6 Unimolecular nucleophilic substitution (SN1)reaction -- 1.7 Bimolecular nucleophilic substitution (SN2)reaction -- 1.8 Neighbouring group participation (NGP) -- 1.9 Substitution nucleophilic internal (SNi) Mechanism -- 1.10 Nucleophilic aromatic substitution -- 1.10.1 Addition-elimination mechanism (An activatedcomplex mechanism) -- 1.10.2 Elimination-addition mechanism (Benzyne mechanism) -- 1.11 Electrophilic aliphatic, alkenyl, and alkynyl substitution reaction -- 1.11.1 Unimolecular electrophilic aliphatic substitution (SE1) reaction…”
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