Molecular imaging : basic principles and applications in biomedical research /

This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how the...

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Bibliographic Details
Main Author: Rudin, M. 1953- (Author)
Format: Electronic eBook
Language:English
Published: London : Imperial College Press, [2013]
Edition:2nd edition.
Subjects:
Online Access:CONNECT

MARC

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100 1 |a Rudin, M.  |q (Markus),  |d 1953-  |e author.  |1 https://id.oclc.org/worldcat/entity/E39PBJvRYRr8G8RwGMBW3Y7mBP 
245 1 0 |a Molecular imaging :  |b basic principles and applications in biomedical research /  |c Markus Rudin, University of Zürich, Switzerland. 
250 |a 2nd edition. 
264 1 |a London :  |b Imperial College Press,  |c [2013] 
264 2 |a Singapore :  |b World Scientific 
264 4 |c ©2013 
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505 0 |a Introduction -- Methodologies -- Imaging techniques -- Molecular reporter systems -- Design of molecular imaging probes -- Applications -- Drug imaging -- Imaging gene expression -- Imaging the function of gene products -- Monitoring of cell migration. 
520 |a This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies. The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts. 
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