Bacteriophages in health and disease /
This book, Bacteriophages in health and disease, is an effort to provide an introduction to the breadth of roles that phages play or can play in our everyday lives. To capture this variety of phage roles in human conditions, both natural and applied, the book is divided into three parts. A brief int...
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Other Authors: | , |
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Format: | Electronic eBook |
Language: | English |
Published: |
Wallingford, Oxfordshire :
CABI,
2012.
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Series: | Advances in molecular and cellular microbiology ;
24. |
Subjects: | |
Online Access: | CONNECT |
MARC
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245 | 0 | 0 | |a Bacteriophages in health and disease / |c edited by Paul Hyman and Stephen T. Abedon. |
264 | 1 | |a Wallingford, Oxfordshire : |b CABI, |c 2012. | |
264 | 4 | |c ©2012 | |
300 | |a 1 online resource (296 pages) : |b illustrations. | ||
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490 | 1 | |a Advances in molecular and cellular microbiology ; |v 24 | |
520 | 3 | |a This book, Bacteriophages in health and disease, is an effort to provide an introduction to the breadth of roles that phages play or can play in our everyday lives. To capture this variety of phage roles in human conditions, both natural and applied, the book is divided into three parts. A brief introduction to various concepts and terminology associated with phages is provided in chapter 1. Part I (chapters 2-6) considers the role of phages in the natural state. That is, where phages are, how they contribute directly to disease, the underlying mechanism by which phages do this, and how they can contribute indirectly to disease, that is, to pathogen evolution. Part II (chapters 7-11) considers various phage-based technologies other than the use of whole phages to combat bacterial infections (i.e. besides phage therapy). This includes in particular the use of both modified and 'disembodied' phage parts. Phages thus can serve as carriers and delivery vehicles of DNA and also of other chemicals, including serving as vectors for either gene therapy or DNA vaccines. Part III (chapters 12-17) covers phage-based antibacterial strategies. It includes chapters on: phage translocation, safety and immunomodulation; phage therapy of wounds and related purulent infections; phage therapy of non-wound infections; phage-based enzybiotics; and phage-based control of bacterial pathogens in food. The final chapter of this book is targeted to would-be phage therapy experimentalists, one that considers, in light of phage properties, how phage therapy protocols may be developed in terms of the use of animal models of bacterial disease. | |
504 | |a Includes bibliographical references and index. | ||
505 | 0 | |a Phages / Stephen T. Abedon -- Bacteriophages as part of the human microbiome / Andrey V. Letarov -- Diseases caused by phages / Sarah Kuhl, Stephen T. Abedon, and Paul Hyman -- Prophage-induced changes in cellular cytochemistry and virulence / Gail E. Christie [and five others] -- The lion and the mouse : how bacteriophages create, liberate, and decimate bacterial pathogens / Heather Hendrickson -- Phages and bacterial epidemiology / Michele L. Williams and Jeffrey T. LeJeune -- Phages as therapeutic delivery vehicles / Jason Clark, Stephen T. Abedon, and Paul Hyman -- Clinical applications of phage display / Don L. Siegel -- Phages and their hosts : a web of interactions: applications to drug design / Jeroen Wagemans and Rob Lavigne -- Bacteriophage-based methods of bacterial detection and identification / Christopher R. Cox -- Phage detection as indication of fecal contamination / Lawrence D. Goodridge and Travis Steiner -- Phage translocation, safety, and immunomodulation / Natasza Olszowska-Zaremba [and three others] -- Phage therapy of wounds and related purulent infections / Catherine Loc-Carrillo, Sijia Wu, and James Peter Beck -- Phage therapy of non-wound infections / Ben Burrowes and David R. Harper -- Phage-based enzybiotics / Yang Shen [and three others] -- Role of phages in control of bacterial pathogens in food / Yan D. Niu [and three others] -- Phage therapy best practices / Stephen T. Abedon. | |
588 | |a Description based on online resource; title from digital title page (ebrary, May 19, 2014). | ||
650 | 0 | |a Bacteriophages. | |
650 | 7 | |a Bacteriophages. |2 fast |0 (OCoLC)fst00825287 | |
700 | 1 | |a Hyman, Paul |q (Paul Lawrence), |e editor. | |
700 | 1 | |a Abedon, Stephen T., |e editor. | |
730 | 0 | |a CABI ebooks Archive, 2011-2013 | |
776 | 0 | 8 | |i Print version: |t Bacteriophages in health and disease. |d Wallingford, Oxfordshire : CABI, ©2012 |z 9781845939847 |w (DLC) 2012007325 |w (OCoLC)778040181 |
830 | 0 | |a Advances in molecular and cellular microbiology ; |v 24. | |
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