Skin tissue engineering and regenerative medicine /
The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and r...
Saved in:
| Other Authors: | , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
London :
Academic Press,
[2016]
|
| Subjects: | |
| Online Access: | CONNECT |
Table of Contents:
- Front Cover; Skin Tissue Engineering and Regenerative Medicine; Copyright; Dedication; Contents; List of Contributors; Foreword; 1
- Anatomy, Physiology, Histology, and Immunohistochemistry of Human Skin; INTRODUCTION; SKIN ANATOMY, HISTOLOGY, AND PHYSIOLOGY; EPIDERMIS; Keratinocytes; Melanocytes; Langerhans Cells; Merkel Cells; DERMOEPIDERMAL JUNCTION; DERMIS; Vasculature; Muscles; Nerves; Skin Appendages; HYPODERMIS; WOUND HEALING AND IMMUNOHISTOCHEMISTRY; Wound Morphometrics; Immunohistochemistry to Define Elements within the Skin; REFERENCES.
- 2
- Molecular and Cellular Biology of Wound Healing and Skin RegenerationINTRODUCTION; Normal Adult Wound Healing; Scarless Fetal Healing; Scarless Wound Healing in/ he Adult; FIBROPROLIFERATIVE DISORDERS OF/ HE SKIN; Cellular Basis of HTS; Molecular Basis of HTS; Lessons Learned from Preclinical Porcine Models of Abnormal/ kin Healing; MEDICAL THERAPIES FOR SKIN REGENERATION; Commercially Available Tissue-Engineered Skin Solutions/ or HTS; Recent Developments/ n Dermal Engineering; FUTURE DIRECTIONS; LIST OF ABBREVIATIONS; ACKNOWLEDGMENTS; REFERENCES.
- 3
- Tissue Processing and Staining for Histological AnalysesINTRODUCTION; TISSUE FIXATION; TISSUE PROCESSING AND EMBEDDING; HEMATOXYLIN AND EOSIN STAIN; BRIGHT FIELD MICROSCOPY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; Antibodies Commonly Used/ or Skin Disorders; HISTOCHEMICAL STAINS; Trichrome Stain; GMS Stain (Methenamine/ ilver-Grocott's); Phosphotungstic Acid-Hematoxylin, Mallory's; PAS Stain (McManus' Periodic Acid-Schiff's); Elastic Tissue Fibers-Verhoeff's Van Gieson; Acid-Fast Bacteria-Ziehl-Neelsen Stain; CONCLUSION; REFERENCES.
- 4
- Clinical Management of Wound Healing and Hypertrophic ScarringWOUND HEALING AND THE BIOMEDICAL BURDEN OF ITS DYSFUNCTION; STAGES OF WOUND HEALING; PATHOLOGIC WOUND HEALING; CHRONIC WOUNDS; WOUND HEALING THERAPIES; Negative Pressure Therapy; Cytokines and Growth Factors; Cell-Based Therapy; Biomimetic Scaffolds; FIBROPROLIFERATIVE DISEASE; SCAR REDUCTION THERAPIES; General Approaches; Scar Revision Surgery; Radiotherapy; Laser Therapy; Cryotherapy; Moisture-Retaining Dressings; Antiproliferative Agents; Anti-inflammatory Therapies; Reducing Mechanical Tension; REGENERATIVE HEALING.
- CONCLUSIONLIST OF ABBREVIATIONS; REFERENCES; 5
- Process Development and Manufacturing of Human and Animal Acellular Dermal Matrices; INTRODUCTION; CLINICAL NEED; DEVELOPMENT OF ADMS; ADM REQUIREMENTS; PROCESSING METHODOLOGIES; Tissue Acquisition; Animal Dermis; Human Dermis; Decellularization Techniques; Physical Methods; Chemical Methods; Detergents; Acids or Bases; Hypotonic or Hypertonic Treatments; Alcohol and Other Solvents; Biologic Methods; Decellularization Criteria; Crosslinking; Preservation of ADMs; Wet Preservation; Cryopreservation; Freezing; Lyophilization; Sterilization.
